Academic Title
Major Area(s) of Study
Assistant Clinical Professor UCSD Neuropsychology
Address 619-471-3925 410 Dickinson Street, Suite 100 / San Diego, CA 92103

Graduate Institution

SDSU/UCSD Joint Doctoral Program in Clinical Psychology

Research Description

Dr. Nguyen’s research aims to identify biological mechanisms underlying cognitive and brain aging in severe mental illness. She is interested in how inflammatory processes may impact brain systems and cognition in people with schizophrenia and bipolar disorder. Her current work has been focused on the role of the gut microbiome in schizophrenia and how imbalance of the gut ecosystem can alter immune responses and lead to alterations to brain and behavioral function via the “gut-brain axis.” She is also interested in exploring interventions that may target inflammation and gut mechanisms to improve cognitive outcomes.

Representative Publications
  • Nguyen, T. T., Kosciolek, T., Eyler, L. T., Knight, R., & Jeste, D. V. (2018). Overview and Systematic Review of Studies of Microbiome in Schizophrenia and Bipolar Disorder. Journal of Psychiatric Research, 99, 50-61.

  • Nguyen, T. T., Eyler, L. T., & Jeste, D. V. (2018). Systemic Biomarkers of Accelerated Aging in Schizophrenia: A Critical Review and Future Directions. Schizophrenia Bulletin, 44, 398-408.

  • Dev, S. I., Nguyen, T. T., McKenna, B. K., Sutherland, A. N., Bartsch, H. Theilmann, R. J., & Eyler, L. T. (2017). Steeper slope of age-related changes in white matter microstructure and processing speed in bipolar disorder. American Journal of Geriatric Psychiatry, 7, 744-752.


Dilip Jeste / Lisa Eyler / Rob Knight