Academic Title
Major Area(s) of Study
Professor in Residence, Psychiatry UCSD Neuropsychology
Address 858-534-2678 8950 Villa La Jolla Drive / Multimodal Imaging Laboratory (Suite C101) / La Jolla, CA 92037

Graduate Institution

University of Florida

Research Description

Dr. McDonald’s research focuses on understanding neuropsychological deficits in patients with intractable epilepsy before and after surgical resection of the epileptic focus. Her research uses advanced structural, diffusion, and functional neuroimaging to explore the localization of language and memory processing in patients with epilepsy, with the goal of determining the best predictors of postsurgical outcome. Her research goals are aligned with the clinical goal of developing and implementing new cognitive/imaging paradigms for clinical use. She is also involved in neuroimaging and neuropsychological research in patients with Alzheimer’s disease and mild cognitive impairment, as well as research examining the application of new, advanced diffusion methods for the detection and monitoring of brain tumors in patients with high-grade gliomas and cerebral metastases.

Representative Publications
  • Edmonds EC, McDonald CR, Marshall A, Thomas KR, Eppig J, Weigand AJ, Delano-Wood L, Galasko DR, Salmon DP, Bondi MW. Early versus late MCI: Improved MCI staging using a neuropsychological approach. Alzheimers Dement. 2019 Feb 05. PMID: 30737119.

  • Tringale KR, Nguyen T, Bahrami N, Marshall DC, Leyden KM, Karunamuni R, Seibert TM, Kay Gorman M, Connor M, Burkeen J, Piccioni DE, Farid N, Hattangadi-Gluth JA, McDonald CR. Identifying early diffusion imaging biomarkers of regional white matter injury as indicators of executive function decline following brain radiotherapy: A prospective clinical trial in primary brain tumor patients. Radiother Oncol. 2019 Mar; 132:27-33. PMID: 30825966.

  • Ehrlich T, Reyes A, Paul BM, Uttarwar V, Hartman S, Mathur K, Chang YA, Hegde M, Shih JJ, McDonald CR. Beyond depression: The impact of executive functioning on quality of life in patients with temporal lobe epilepsy. Epilepsy Res. 2019 Jan; 149:30-36. PMID: 30468945.


Anders M. Dale, Ph.D. / Eric Halgren, Ph.D. / Mark Bondi, Ph.D. / Lisa Delano-Wood, Ph.D.